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[DOI] [PubMed] [Google Scholar] 55.Schwope DM, Karschner EL, Gorelick DA, Huestis MA
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FoxO promotes the expression of atrophy-related genes (atrogenes), and under critical conditions such as sepsis, decreased IGF-1-PI3K-Akt-mTOR signaling increases FoxO-mediated expression of atrogenes, reducing protein synthesis (81-83)